The use of recombinant antibodies in proteomics

Recombinant antibodies are becoming increasingly important in the field of proteomics. Recent advances include the development of large phage-antibody libraries that contain high-affinity binders to almost any target protein, and new methods for high-throughput selection of antibody-antigen interact ions. Coupled with a range of new screening technologies that use high-dens ity antibody arrays to identify differentially expressed proteins, these an tibody libraries can be applied to whole proteome analysis.