A 73-year-old man with porokeratosis palmaris, plantaris et disseminata is
presented. He had punctate, guttate and annular hyperkeratotic papular lesi
ons widespread on his body with thorn-like hyperkeratosis on the palms and
soles. Lesional skin did not show mutations of TP53 exons 5-6, 7, 8. Copyri
ght (C) 2000 S. Karger AG, Basel.