S. Niemann et al., Double infection with a resistant and a multidrug-resistant strain of Mycobacterium tuberculosis, EM INFECT D, 6(5), 2000, pp. 548-551
An immunocompetent patient was dually infected with a resistant and a multi
drug-resistant strain of Mycobacterium tuberculosis (TB). The multidrug-res
istant strain, which belongs to the W-strain/Beijing family, was first isol
ated after 3 months of therapy. Inappropriate treatment led to further drug
resistance and unsuccessful therapy. Thus, additional infections with resi
stant M. tuberculosis strains should be considered when tuberculosis therap
y fails.