Micropapillary serous carcinoma of the ovary: Case report and review of literature

The term "micropapillary serous carcinoma" (MPSC) has recently been introdu ced to define a subset of ovarian serous borderline turners morphologically characterized by a micropapillary pattern and clinically associated with a more aggressive behavior than that of the typical ovarian serous borderlin e tumors. Ovarian MPSC's are associated with extra-ovarian invasive periton eal implants and invasive recurrences much more frequently than typical ova rian serous borderline tumors. The case of a women, who at age 28 had bilat eral ovarian cystectomy and four months later total abdominal hysterectomy and bilateral salpingo-oophorectomy for bilateral ovarian MPSC, is reported . She was free of disease for the next 15 years and then presented with a c entral pelvic mass. At laparotomy, a recurrence in the form of a solitary i nvasive peritoneal implant was discovered and completely resected. No posto perative adjuvant therapy was given. To date, 16 years after initial diagno sis of MPSC, and one year after detection of recurrence, the patient is ali ve, well and without disease. Literature data and this case report support the view that MPSC's should be classified separately from both typical sero us borderline tumors and invasive carcinomas of the ovary.