Uterine rupture associated with vaginal birth after cesarean section: A complication of intravaginal misoprostol?

Intravaginal misoprostol has become increasingly employed for labor inducti on among patients with an unfavorable Bishop's score. Almost all of the rep orted studies have specifically excluded patients with prior uterine surger y. There has been, therefore, very little information concerning its usage among patients attempting vaginal birth after cesarean section. We report a patient with two prior low transverse uterine incisions who experienced ut erine rupture after having received a single 25-mu g intravaginal dose of m isoprostol, Copyright (C) 2000 S. Karger AG, Basel.