The regulation of the human corpus luteum steroidogenesis: a hypothesis?

Authors
Oon, VJH Johnson, MR
Citation
Vjh. Oon et Mr. Johnson, The regulation of the human corpus luteum steroidogenesis: a hypothesis?, HUM REP UPD, 6(5), 2000, pp. 519-529
Citations number
48
Categorie Soggetti
Reproductive Medicine
Journal title
HUMAN REPRODUCTION UPDATE
ISSN journal
13554786 → ACNP
Volume
6
Issue
5
Year of publication
2000
Pages
519 - 529
Database
ISI
SICI code
1355-4786(200009/10)6:5<519:TROTHC>2.0.ZU;2-P
Abstract
The corpus luteum (CL) is an important endocrine organ in the menstrual cyc le and in pregnancy. The regulation of its hormonal production has been ext ensively studied. The steroidogenic abilities of the CL can be rescued by h uman chorionic gonadotrophin (HCG) but its role in the maintenance of CL fu nction is not clear. We will discuss the hypothesis that there are fetoplac ental factors, other than HCG, that modulate CL steroidogenesis.