Y. Habata et al., Synthesis of armed and double-armed macrocyclic ligands by the Mannich reaction: A short review, IND ENG RES, 39(10), 2000, pp. 3465-3470
The Mannich reaction is useful in the chemical industry because of its wide
applicability to organic synthesis. This short review summarizes some rece
nt work (1996-2000) on the synthesis of new armed and double-armed macrocyc
lic ligands using the Mannich reaction, presents a study concerning side re
action products, and discusses reaction mechanisms.