STRUCTURE-ACTIVITY-RELATIONSHIPS OF SANDALWOOD ODORANTS - SYNTHESIS AND ODOR OF METHYL-BETA-SANTALOL .40.

Authors
BUCHBAUER G ZECHMEISTERMACHHART F WEISSGREILER P WOLSCHANN P
Citation
G. Buchbauer et al., STRUCTURE-ACTIVITY-RELATIONSHIPS OF SANDALWOOD ODORANTS - SYNTHESIS AND ODOR OF METHYL-BETA-SANTALOL .40., Archiv der pharmazie, 330(4), 1997, pp. 112-114
Citations number
14
Categorie Soggetti
Chemistry,"Pharmacology & Pharmacy
Journal title
Archiv der pharmazie → ACNP
ISSN journal
03656233
Volume
330
Issue
4
Year of publication
1997
Pages
112 - 114
Database
ISI
SICI code
0365-6233(1997)330:4<112:SOSO-S>2.0.ZU;2-#
Abstract
The synthesis and odour properties of the new santalol analogue, methy l-beta-santalol, are described. The additional methyl group adjacent t o the hydroxyl function of the standard molecule, beta-santalol, depri ves the new compound of the sandalwood note. The synthesis and the odo ur evaluation of this compound supports the proposed model for sandalw ood fragrance as it shows that the methyl group located at the osmopho ric center prevents association of the molecule with the hypothetical receptor.