Amiodarone-related optic neuropathy

Background: To evaluate a case of atypical optic neuropathy that presented with blurred vision following the use of an antiarrythmic agent. Case: Record of the patient was reviewed to determine the etiology of his o ptic neuropathy. Observations: Ophthalmological examination revealed unilateral optic disc e dema with relatively well-preserved visual acuity. In routine tests, result s of complete blood count, erythrocyte sedimentation rate, liver and kidney function tests, chest x-ray, Goldmann visual field examination, and brain computed tomography scan were normal. Orbital ultrasonography revealed opti c disc edema with prominent optic nerve head and without orbital pathology. Conclusions: Systemic history and drug intake should be investigated in eve ry patient with optic disc edema. Discontinuation of the medication can pre vent further optic nerve damage or involvement of the other eye. (C) 2000 J apanese Ophthalmological Society.