Systolic pressure variations (SPV) during mechanical ventilation and its si
ngle components, related to short apnea, reflect changes of the volemic con
dition of the patient. To introduce their determination during clinical mon
itoring for different fluid states and for different tidal volumes, they mu
st be computed on-line without introducing interference with standard activ
ities. A system computing on-line systolic pressure variation du ring mecha
nical ventilation, connected to standard monitoring devices, has been propo
sed. It is based on a notebook PC implemented with graphical software compr
ising a user panel in the form of a virtual instrument and is able to acqui
re, process and present signals from different instruments utilized in ICU
and during surgery. It can be used as a base to assess the ability of compu
ted parameters helpful in clinical decision. The use of a notebook PC and o
pen software allows operators, even if non-expert in computer science, to t
est and implement this, as well as other innovative tools in clinical pract
ice.