Use of unconventional therapies by children with cancer at an urban medical center

Purpose: The aim of this study was to determine the prevalence, modalities, and determinants of use of unconventional therapies among children with ca ncer receiving conventional treatment at an urban academic medical center i n the United States. Patients and Methods: We interviewed the parents of patients and/or patient s who were receiving or had received conventional therapy for treatment of childhood cancer. Of 78 patients/parents asked, 75 consented to the intervi ew, which included demographic factors, life events, and use of unconventio nal therapies. All participants also consented to the abstraction of chart data for this study. Results: Overall, 84% of respondents reported the use of one or more unconv entional therapies. The most commonly used modalities were changes in diet, nutritional and herbal agents, and mind/body treatments. Most users had tr ied more than one unconventional modality. No difference in use was seen by cancer, diagnosis, race/ethnicity, socio-economic status, or educational a ttainment of the respondent. Of the therapies used, 50% were not reported t o the physicians. Of patients reporting use of an unconventional approach, 85% were concurrently enrolled on clinical trials for primary treatment of their cancer. Conclusions: The use of unconventional therapies is highly prevalent among children with cancer and is not associated with demographic or clinical fac tors or participation in clinical trials. The possibility that an unconvent ional treatment may interact with a protocol treatment underscores the need for more information about the use of such therapies among all patients.