Various-sized stearyl poly(ethylene oxide) coupling-polymer blending poly(ether urethane) material for surface study and biomedical applications

Three types of stearyl poly(ethylene oxide) with different values of M-n, 2 300, 6000 and 12000, were synthesized by an anion polymerization from the e thylene oxide (EO) monomer with the initiator, sodium salt of stearyl alcoh ol. Consequently the amphiphilic coupling polymers of 4,4'-diphenylmethane diiso-cyanate (MDI)-SPEO (SPEO-MDI-SPEO, MSPEO 2300, 6000 and 12000) were s ynthesized and the blended polyurethane) samples of PELMSPEOs (PEL-MSPEO 60 00 and 12000) were prepared via a solution process. The surface analysis wi th ATR-FTIR, angle-dependent XPS and two methods of contact angle measureme nts (sessile drop and captive bubble) were performed. The results of the an alysis indicate that the dominant factor for the monoblock behavior of long -chained MSPEO 12000 is the PEO chain. However, for shea-chained MSPEO the factor is C-18 and the dominant effect is not so overwhelming compared to t hat of PEO for long-chained MSPEO. Simultaneously, the size of the molecule will also dramatically affect MSPEOs' kinetic behavior including the monob lock mobility and the reconstructing of the surface a, i.e. the smaller the size, the faster the The static test of clotting time, PRT, was also med T he results indicated that the modified surface resist the clotting much mor e effectively than thatof the untreated surface.