Synthesis of some new pyrimido[5,4-a]indolizines

Authors
Abd El-Salam, OI
Citation
Oi. Abd El-salam, Synthesis of some new pyrimido[5,4-a]indolizines, MONATS CHEM, 131(9), 2000, pp. 959-965
Citations number
5
Categorie Soggetti
Chemistry
Journal title
MONATSHEFTE FUR CHEMIE
ISSN journal
00269247 → ACNP
Volume
131
Issue
9
Year of publication
2000
Pages
959 - 965
Database
ISI
SICI code
0026-9247(200009)131:9<959:SOSNP>2.0.ZU;2-L
Abstract
The synthesis of new pyrimido[5,4-a]indolizines by reaction of 2-aminoindol izine-1-carbonitrile or ethyl 2-aminoindolizine-1-carboxylate with various electrophilic reagents is described. The structure of the products was conf irmed by their elemental analysis and IR, H-1 NMR, and mass spectra. The re sults of a preliminary antimicrobial screening are also presented.