AGGRESSIVE GIANT KERATOACANTHOMA OF THE FACE TREATED WITH INTRAMUSCULAR METHOTREXATE AND TRIAMCINOLONE ACETONIDE

Authors
SANTOSOPHAM JC SHELLEY ED SHELLEY WB
Citation
Jc. Santosopham et al., AGGRESSIVE GIANT KERATOACANTHOMA OF THE FACE TREATED WITH INTRAMUSCULAR METHOTREXATE AND TRIAMCINOLONE ACETONIDE, Cutis, 59(6), 1997, pp. 329-332
Citations number
25
Categorie Soggetti
Dermatology & Venereal Diseases
Journal title
Cutis → ACNP
ISSN journal
00114162
Volume
59
Issue
6
Year of publication
1997
Pages
329 - 332
Database
ISI
SICI code
0011-4162(1997)59:6<329:AGKOTF>2.0.ZU;2-V
Abstract
Keratoacanthoma is a common skin tumor characterized by rapid growth o f a smooth dome-shaped nodule with a central plug of keratin, usually followed by spontaneous involution. We report the case of a giant kera toacanthoma on the face that continued to spread peripherally for seve ral months despite vigorous therapeutic intervention. Treatment with m ethotrexate (25 mg intramuscularly) and Kenalog(R) (triamcinolone acet onide, 40 mg intramuscularly) weekly finally slowed and stopped the ex panding, deforming tumor growth and induced involution.