T cell development: Some cells get all the breaks

Authors
Green, DR Schuler, M
Citation
Dr. Green et M. Schuler, T cell development: Some cells get all the breaks, NAT IMMUNOL, 1(1), 2000, pp. 15-17
Citations number
15
Categorie Soggetti
Immunology
Journal title
NATURE IMMUNOLOGY
ISSN journal
15292908 → ACNP
Volume
1
Issue
1
Year of publication
2000
Pages
15 - 17
Database
ISI
SICI code
1529-2908(200007)1:1<15:TCDSCG>2.0.ZU;2-U
Abstract
Without Brca I, T cells are lacking in numbers and maturity, but surprising ly not because of a lack of repair of rearranged TCR genes,The defects invo lve more than one p53-dependent mechanism.