An Epstein-Barr virus-associated pulmonary lymphoproliferative disorder ascomplication of immunosuppression

Inherited or acquired immunodeficiencies as well as autoimmune diseases tre ated with cytotoxic drugs are associated with an increased incidence of lym phoma. Non-Hodgkin's lymphomas that occur in the context of drug-induced im munosuppression, acquired or congenital immunodeficiency, are frequently as sociated with Epstein-Barr virus infection. This report describes the occur rence of an Epstein-Ban virus associated pulmonary B cell lymphoma in a pat ient with longstanding rheumatoid arthritis treated with methotrexate. (C) 2000 Elsevier Science BN. All rights reserved.