Correlations between reaction time and cerebral blood flow during motor preparation

Citation
B. Horwitz et al., Correlations between reaction time and cerebral blood flow during motor preparation, NEUROIMAGE, 12(4), 2000, pp. 434-441
Citations number
47
Categorie Soggetti
Neurosciences & Behavoir
Journal title
NEUROIMAGE
ISSN journal
10538119 → ACNP
Volume
12
Issue
4
Year of publication
2000
Pages
434 - 441
Database
ISI
SICI code
1053-8119(200010)12:4<434:CBRTAC>2.0.ZU;2-1
Abstract
We show using positron emission tomography in normal volunteers that for fo ur tasks involving motor preparation, regional cerebral blood flow in the i psilateral cerebellum is negatively correlated with reaction time. Each of the tasks presented subjects with different amounts of advanced information (from none to partial to full information) prior to a signal. to move one of two possible fingers in one of two possible directions. The cerebellum w as the only brain area that was correlated with reaction time in all the co nditions. These results are compatible with the idea that the cerebellum pl ays an important role in the preparation and initiation of motion.