In this research we examined hormonal correlates of hand preference in free
-ranging primates. Specifically, we tested the hypothesis that levels oft h
e stress hormone cortisol nod the male sex hormone testosterone are correla
ted with handedness in male rhesus macaques (Macaca mulatta). We found sign
ificant positive relationships between cortisol and testosterone levels sam
pled during adolescnece ann the frequency of right- versus left-hand use sa
mpled during adulthood. These data indicate that adolescent measures of cor
tisol and testosterone are correlated with hemispheric specialization in ad
ult free-ranging primates.