The two main approaches currently used for surgical treatment of esoph
ageal cancer are transhiatal esophagectomy (THE) and esophagectomy thr
ough a right thoracotomy. Among technical variations of THE, wide open
ing of the diaphragm with ample mediastinal exposure allows resection
under direct view with acceptable postoperative morbidity and mortalit
y rates. Transthoracic esophagectomy associated with extensive mediast
inal lymphadenectomy, still offers the best chance of definitive cure
in intermediate stages (stages II and III), but does not influence sur
vival in advanced cases (stage IV). In early stages, the lymph node in
vasion rate is negligible and may be treated by other techniques (THE
or endoscopic mucosectomy). THE restores oral ingestion and avoids res
piratory complications of thoracotomy, and consequently can be reserve
d for early cases (mucosal or submucosal lesions) or for patients with
poor clinical status. To improve results of surgical treatment, proto
cols of associated radiochemotherapy are currently under research. (C)
1997 Wiley-Liss, Inc.