Objective. The purpose of this prospective, randomized, blinded study was t
o determine the effect of trephination on postoperative pain and swelling i
n symptomatic necrotic teeth.
Study design. Fifty emergency patients participated, and each had a clinica
l diagnosis of a symptomatic necrotic tooth with associated periapical radi
olucency. After endodontic treatment, patients randomly received either a t
rephination or mock trephination procedure. The trephination procedure used
an intraosseous perforator to provide an initial opening in the cortical b
one that was enlarged with files (No. 25 through No. 70) and an endodontic
spoon. After surgery each patient received ibuprofen; acetaminophen with co
deine (30 mg); and a 7-day diary to record pain, percussion pain, swelling,
and number and type of pain medication taken.
Results. The majority of patients with symptomatic necrotic teeth had signi
ficant postoperative pain and required analgesics to manage this pain. The
use of a trephination procedure with an intraosseous perforator, files, and
a spoon excavator did not significantly reduce pain, percussion pain, swel
ling, or the number of analgesic medications taken in symptomatic necrotic
teeth with periapical radiolucencies (P > .05).
Conclusion. We cannot recommend the routine use of a trephination procedure
, as used in this study, for relief of pain in symptomatic necrotic teeth w
ith radiolucencies.