Hydroxyapatite (HA) middle ear prostheses have gained popularity as an alte
rnative to human autografts and homografts, This study reports on 3 HA pros
theses types: total ossicular chain prostheses, used for grafting the stape
s footplate to the tympanic membrane; partial ossicular chain prostheses, u
sed for grafting the stapes superstructure to the tympanic membrane; and Ka
rtush incus struts (Smith & Nephew Richards Inc), used for grafting the sta
pes superstructure to the undersurface of the malleus, This single-surgeon
study of 33 consecutive cases revealed a statistically significant differen
ce in mean postoperative air-bone gap and air-bone gap closure between incu
s struts (14/26 dB) or partial (22/11 dB) or total (25/10 dB) ossicular cha
in prostheses (t test: P < 0.05), Prognostic risk factors graded by the Mid
dle Ear Risk Index indicate a tendency for worse postoperative hearing with
increasing Middle Ear Risk Index. This study supports the use of HA ossicu
lar prostheses and, in particular, the use of the malleus for ossicular cha
in construction.