Macrophage activation syndrome (MAS) is a rare disorder characterised by be
nign, reactive, excessive, well-differentiated macrophage proliferation, se
condary to an immune dysregulation in response to some triggering agents su
ch as viral infection. We report a 3-year-old girl with MAS and pulmonary i
nvolvement. This is the first radiographic description of MAS on high-resol
ution CT.