To the macro- and microcirculation on the fore foot under different compression pressure in healthy female probands

Aim and methods: The aim of this study was to investigate the macro- and mi crocirculation on the fare foot of healthy Female probands undergoing dosed compression of whole leg. The macro- and microcirculation were investigate d using a combination of measuring ankle pressure by means of doppler ultra sound, near-infrared-red-remission-photoplethsymography (NIRP) resp. laser doppler flowmetry (LDF), transcutaneous measuring of oxygen.(tcpO(2)) and c orbondioxyde pressure (tcpCO(2)) and NIRP-method before and after 5 minutes compression with 10, 20, 30, 40 resp. 50 ton under resting conditions in a total of 13 healthy women, mean age 33,4 +/- 16,8 years. Results: Ankle pr essure, tcpO(2), tcpCO(2) were nearly constant. LDF-flux and hematocrit sho wed an significant downward (p <0,01 rsp. p <0,05) with rising compression pressure above 20 tori. The peripheral microcirculatory coefficient pMC est imated by means of NIRP-method was reduced significantly (p <0,05) above a compression pressure of 10 torr. The spectral number M(LF)o was changed sca rcely whereas the number M(LF)v was rising significantly (p <0,05 rsp. 0,01 ). The pulse ration PQ was reduced significantly (p <0,05) whereas the peak time T-G and the turning-paint time T-W were reduced significantly (p <0,0 1) above 10 resp. 30 torr. Conclusion: In healthy probands a compression pr essure up to 50 torr does not lead to a detoriation in the macrocirculation but there will be on influence of compression to the microcirculation.