Using spatially resolved, steady state diffuse reflectometry, a directional
dependence was found in the propagation of visible and near infrared light
through human skin in vivo. The skin's reduced scattering coefficient mu(s
)' varies by up to a factor of two between different directions of propagat
ion at the same position. This anisotropy is believed to be caused by the p
referential orientation of collagen fibres in the dermis, as described by L
anger's skin tension lines. Monte Carlo simulations that examine the effect
of partial collagen fibre orientation support this hypothesis. The observa
tion has consequences for non-invasive diagnostic methods relying on skin o
ptical properties, and it could be used non-invasively to determine the dir
ection of lines of cleavage in order to minimize scars due to surgical inci
sions.