2 DOLABRANE-TYPE DITERPENOIDS

Authors
DAMAS AM KIJJOA A PINTO M
Citation
Am. Damas et al., 2 DOLABRANE-TYPE DITERPENOIDS, Acta crystallographica. Section C, Crystal structure communications, 53, 1997, pp. 755-757
Citations number
10
Categorie Soggetti
Crystallography
Journal title
Acta crystallographica. Section C, Crystal structure communications → ACNP
ISSN journal
01082701
Volume
53
Year of publication
1997
Part
6
Pages
755 - 757
Database
ISI
SICI code
0108-2701(1997)53:<755:2DD>2.0.ZU;2-U
Abstract
The crystal structures of two dolabrane diterpenes, ent-2-seco-3-nor-5 alpha,4,15-dioxo-16-hydroxydolabran-2-oic acid, C19H30O5, (I), and en t-2-seco-3-nor-5 alpha,16-chloro-15-hydroxydolabran-2-oic acid, C(19)H (31)C(10)4, (II), have been determined at room temperature. They revea led the presence of two trans-fused rings having a chair conformation and they confirmed previous NMR studies showing that the C9 substituen t is trans with respect to those at C8 and C10. Furthermore, we observ ed that the longer C-Sp3-C-sp3 distances occur for C9-C10 and C5-C10, which is in agreement with the values found in other diterpenes. These are the first reported crystal structures of dolabrane molecules.