Musculoskeletal disorders including arthralgia and myalgia are adverse effe
ct common to all fluoroquinolones. We report a case of spontaneous rupture
of the patellar ligament in a 37-year-old man participating in leisure spor
ts which occurred one month after a three-week course of Ciprofloxacine(R).
Several cases of tendon ruptures have been reported in the literature, inc
luding the patellar tendon. Unusual features in our case were the one-month
delay before tendon rupture and the absence of inaugural signs. We reviewe
d the pathophysiological mechanisms leading to fluoroquinolone-related tend
on rupture as well as the risk factors and discussed proper management. Car
e must be taken-when prescribing fluoroquinolones for patients at risk. Clo
se follow-up is most important.