Efficient resolution of (+/-)-pantolactone by inclusion crystallization with the use of chiral 1,1,2-triphenylethane-1,2-diol

Authors
Vinogradov, MG Kurilov, DV Ferapontov, VA Heise, GL
Citation
Mg. Vinogradov et al., Efficient resolution of (+/-)-pantolactone by inclusion crystallization with the use of chiral 1,1,2-triphenylethane-1,2-diol, RUSS CHEM B, 49(8), 2000, pp. 1483-1484
Citations number
7
Categorie Soggetti
Chemistry
Journal title
RUSSIAN CHEMICAL BULLETIN
ISSN journal
10665285 → ACNP
Volume
49
Issue
8
Year of publication
2000
Pages
1483 - 1484
Database
ISI
SICI code
1066-5285(200008)49:8<1483:ERO(BI>2.0.ZU;2-E
Abstract
Enantioselective formation of crystalline 1 : 1 host-guest complexes with ( R)- or (S)-1,1,2-triphenylethane-1,2-diol as a host compound allows efficie nt preparative resolution of (+/-)-pantolactone. Optically active pantolact ones (98% ee) were obtained in 65-67% yield.