Recent evidence, showing that gender differences in depression and antisoci
al behavior originate in early adolescence, points to the importance of soc
ialization and dimensions of the self in understanding the higher rates of
internalizing disorders among females and higher rates of externalizing dis
orders among males. We review theories and research that link gender strati
fication to dimensions of the self and through this, to gender differences
in disorders. These theories and evidence further suggest that girls and bo
ys differ in the boundaries drawn between the self and others. Ranging from
high degrees of connectedness to high degrees of separation, such boundari
es are conceptualized as people's basic operating assumptions about social
relationships An analysis of empathy provides a preliminary test of the con
tribution of boundary assumptions to explaining gender differences in inter
nalizing and externalizing disorders.