Fifteen patients with splenic abscesses were evaluated between 1985 and 199
5. The most common predisposing factors were remote infection, diabetes mel
litus and heart disease. Common clinical presentations included leucocytosi
s, fever, left upper quadrant abdominal pain and left pleural effusion. Fou
r patients with splenic abscesses smaller than 4 cm in diameter were treate
d with antibiotics alone, and 1 in this treatment group died. Among the 10
patients with splenic abscesses larger than 4 cm in diameter receiving perc
utaneous drainage, 9 (90%) were successfully cured, including 8 with uniloc
ular abscesses and 1 with multilocular abscesses. Two patients underwent sp
lenectomy. In conclusion, percutaneous drainage using ultrasound or compute
d tomography guidance may be recommended as the treatment of choice for spl
enic abscess larger than 4 cm in diameter. Antibiotics alone may sometimes
be considered for splenic abscesses smaller than 4 cm in diameter. Splenect
omy is reserved for those cases where medical treatment has failed.