Laparoscopic splenectomy (LS) is gaining wide acceptance as a safe, effecti
ve alternative to open splenectomy (OS) in the treatment of hematologic dis
orders in adult and pediatric patients, with low conversion rates and compl
ications. The aim of this retrospective case-control study was to compare t
wo cohorts of patients, with similar characteristics, who underwent OS or L
S in a single institution. The medical records of the initial 20 consecutiv
e patients who underwent LS were reviewed and compared with a control group
of 28 patients undergoing OS, matched for age, gender, diagnosis, splenic
size and weight, and American Society of Anesthesiologists score. Data were
collected regarding operative time, blood loss, blood tranfusions, patholo
gic findings, accessory spleen detection, complications, ileus duration, an
d postoperative hospital stay. Nineteen patients underwent attempted LS. On
e procedure (5%) was converted to OS for uncontrolled hilar bleeding. Acces
sory spleens were detected in two cases in the LS group compared with four
cases in the OS group (14%). Mean operative time was 165 minutes (range: 10
0-240 minutes) for LS and 114 minutes (75-180 minutes) for OS (P < 0.001).
In the LS group a regular diet was tolerated 36 hours (range: 24-48 hours)
after surgery compared with 72 hours (range: 48-96 hours) for the OS group
(P < 0.001), and mean postoperative hospital stay was 4.1 days (range: 3-8
days) for LS, compared with 8.1 days (range: 5-12 days) for OS (P < 0.001).
No differences were observed in blood loss, complication rates, or transfu
sion requirements. Compared with OS, LS requires more operative time (showi
ng a learning curve), is comparable in blood loss, transfusion requirements
, complication rates, and detection of accessory spleens and appears to be
superior in terms of return of bowel function and hospital stay.