Penetrating keratoplasty and glaucoma

Glaucoma remains the leading cause of blindness after penetrating keratopla sty. Postkeratoplasty glaucoma was originally described in 1969, and its ma nagement is still controversial. Recent developments in management include newer classes of drugs, surgical procedures, such as trabeculectomy with mi tomycin-C, implantation of glaucoma drainage devices, and cyclodestructive procedures with Nd: YAG and diode lasers. However, the risk of graft failur e continues to be high with all surgical procedures. (C) 2000 by Elsevier S cience Inc. All rights reserved.