A mild and efficient dethioacetalization employing FeCl3 center dot 6H(2)O: Synthesis of DNA-binding pyrrolo[2,1-c][1,4]benzodiazepine ring system and its dimers

Authors
Kamal, A Laxman, E Reddy, PSMM
Citation
A. Kamal et al., A mild and efficient dethioacetalization employing FeCl3 center dot 6H(2)O: Synthesis of DNA-binding pyrrolo[2,1-c][1,4]benzodiazepine ring system and its dimers, SYNLETT, (10), 2000, pp. 1476-1478
Citations number
35
Categorie Soggetti
Organic Chemistry/Polymer Science
Journal title
SYNLETT
ISSN journal
09365214 → ACNP
Issue
10
Year of publication
2000
Pages
1476 - 1478
Database
ISI
SICI code
0936-5214(200010):10<1476:AMAEDE>2.0.ZU;2-T
Abstract
A simple and efficient dethioacetalization has been carried out by employin g FeCl3 . 6H(2)O under mild conditions. This method has been investigated f or the synthesis of DNA-interactive pyrrolo[2,1-c][1,4]benzodiazepine antit umour antibiotics via deprotective cyclization process.