Simple and efficient preparation of enantiopure alkyl alpha-hydroxyalkyl ketones

Authors
Ferrero, M Galobardes, M Martin, R Montes, T Romea, P Rovira, R Urpi, F Vilarrasa, J
Citation
M. Ferrero et al., Simple and efficient preparation of enantiopure alkyl alpha-hydroxyalkyl ketones, SYNTHESIS-S, (11), 2000, pp. 1608-1614
Citations number
36
Categorie Soggetti
Chemistry & Analysis","Organic Chemistry/Polymer Science
Journal title
SYNTHESIS-STUTTGART
ISSN journal
00397881 → ACNP
Issue
11
Year of publication
2000
Pages
1608 - 1614
Database
ISI
SICI code
0039-7881(200010):11<1608:SAEPOE>2.0.ZU;2-1
Abstract
The acylation reaction of organolithium reagents with pyrrolidine-derived a lpha-benzyloxy and alpha-silyloxy carboxamides provides a simple and high-y ielding method for the preparation of enantiopure alpha-benzyloxy and alpha -silyloxy ketones.