Hypophosphorous acid-iodine: a novel reducing system. Part 1: Reduction ofdiaryl ketones to diaryl methylene derivatives

Authors
Hicks, LD Han, JK Fry, AJ
Citation
Ld. Hicks et al., Hypophosphorous acid-iodine: a novel reducing system. Part 1: Reduction ofdiaryl ketones to diaryl methylene derivatives, TETRAHEDR L, 41(41), 2000, pp. 7817-7820
Citations number
18
Categorie Soggetti
Chemistry & Analysis","Organic Chemistry/Polymer Science
Journal title
TETRAHEDRON LETTERS
ISSN journal
00404039 → ACNP
Volume
41
Issue
41
Year of publication
2000
Pages
7817 - 7820
Database
ISI
SICI code
0040-4039(20001007)41:41<7817:HAANRS>2.0.ZU;2-5
Abstract
A mixture of hypophosphorous acid (H3PO2) and iodine in hot acetic acid red uces diaryl ketones quickly and aryl alkyl ketones slowly to the correspond ing methylene derivatives. The active reducing agent is hydrogen iodide, ge nerated by reaction between iodine and hypophosphorous acid. (C) 2000 Elsev ier Science Ltd. All rights reserved.