Citation
Sl. Colletti et al., Tryptophan-replacement and indole-modifed apicidins: synthesis of potent and selective antiprotozoal agents, TETRAHEDR L, 41(41), 2000, pp. 7825-7829
Citations number
26
Categorie Soggetti
Chemistry & Analysis","Organic Chemistry/Polymer Science
Journal title
TETRAHEDRON LETTERS
ISSN journal
00404039
→ ACNP
Volume
41
Issue
41
Year of publication
2000
Pages
7825 - 7829
Database
ISI
SICI code
0040-4039(20001007)41:41<7825:TAIASO>2.0.ZU;2-Y
Abstract
A ruthenium tetraoxide catalyzed degradation of apicidin's tryptophan indol
e provided access to two useful carboxylic acid homolog intermediates. The
synthesis of a series of potent and/or selective ketone homologs and 2-aryl
indoles derived from apicidin is described. (C) 2000 Elsevier Science Ltd.
All rights reserved.