First synthesis of 3,3-difluoroserine and cysteine derivatives via Mg(0)-promoted selective C-F bond cleavage of trifluoromethylimines

Authors
Mae, M Amii, H Uneyama, K
Citation
M. Mae et al., First synthesis of 3,3-difluoroserine and cysteine derivatives via Mg(0)-promoted selective C-F bond cleavage of trifluoromethylimines, TETRAHEDR L, 41(41), 2000, pp. 7893-7896
Citations number
23
Categorie Soggetti
Chemistry & Analysis","Organic Chemistry/Polymer Science
Journal title
TETRAHEDRON LETTERS
ISSN journal
00404039 → ACNP
Volume
41
Issue
41
Year of publication
2000
Pages
7893 - 7896
Database
ISI
SICI code
0040-4039(20001007)41:41<7893:FSO3AC>2.0.ZU;2-7
Abstract
3,3-Difluoroserine and cysteine derivatives were synthesized via Mg(0)-prom oted defluorination of trifluoromethylimines as a key step, followed by add ition of alcohols and sulfenyl chloride, respectively. (C) 2000 Elsevier Sc ience Ltd. All rights reserved.