A facile synthesis of N-benzylallylglycine

Authors
Bennett, DJ Hamilton, NM
Citation
Dj. Bennett et Nm. Hamilton, A facile synthesis of N-benzylallylglycine, TETRAHEDR L, 41(41), 2000, pp. 7961-7964
Citations number
21
Categorie Soggetti
Chemistry & Analysis","Organic Chemistry/Polymer Science
Journal title
TETRAHEDRON LETTERS
ISSN journal
00404039 → ACNP
Volume
41
Issue
41
Year of publication
2000
Pages
7961 - 7964
Database
ISI
SICI code
0040-4039(20001007)41:41<7961:AFSON>2.0.ZU;2-C
Abstract
N-Benzylallylglycine can be prepared in good yield through a one-pot reacti on of N-benzylhomoallylamine with glyoxylic acid monohydrate in methanol. T he reaction method described requires only mild conditions and avoids the n eed for purification of the amino acid product. (C) 2000 Elsevier Science L td. All rights reserved.