Syntheses of carbon-carbon linked carboranylated porphyrins for boron neutron capture therapy of cancer

Authors
Vicente, MGH Shetty, SJ Wickramasinghe, A Smith, KM
Citation
Mgh. Vicente et al., Syntheses of carbon-carbon linked carboranylated porphyrins for boron neutron capture therapy of cancer, TETRAHEDR L, 41(40), 2000, pp. 7623-7627
Citations number
25
Categorie Soggetti
Chemistry & Analysis","Organic Chemistry/Polymer Science
Journal title
TETRAHEDRON LETTERS
ISSN journal
00404039 → ACNP
Volume
41
Issue
40
Year of publication
2000
Pages
7623 - 7627
Database
ISI
SICI code
0040-4039(20000930)41:40<7623:SOCLCP>2.0.ZU;2-F
Abstract
Total syntheses of six carboranyl-containing porphyrins bearing 33-44% boro n by weight for potential application in boron neutron capture therapy of t umors, are described; these novel compounds feature carbon-carbon linkages between the carboranyl groups and the meso-phenyl substituents. (C) 2000 Pu blished by Elsevier Science Ltd.