Cyclization of hydroxy epoxides promoted by (Bu3Sn)(2)O/Lewis acid: efficient synthesis of oxepanes

Authors
Matsumura, R Suzuki, T Sato, K Oku, K Hagiwara, H Hoshi, T Ando, M Kamat, VP
Citation
R. Matsumura et al., Cyclization of hydroxy epoxides promoted by (Bu3Sn)(2)O/Lewis acid: efficient synthesis of oxepanes, TETRAHEDR L, 41(40), 2000, pp. 7701-7704
Citations number
23
Categorie Soggetti
Chemistry & Analysis","Organic Chemistry/Polymer Science
Journal title
TETRAHEDRON LETTERS
ISSN journal
00404039 → ACNP
Volume
41
Issue
40
Year of publication
2000
Pages
7701 - 7704
Database
ISI
SICI code
0040-4039(20000930)41:40<7701:COHEPB>2.0.ZU;2-9
Abstract
Cyclization of hydroxy epoxides mediated by a (Bu3Sn)(2)O/Lewis acid system proceeded via an S(N)2 process and exo mode to provide the corresponding s even-membered cyclic ethers in high yield. (C) 2000 Elsevier science Ltd. A ll rights reserved.