New bis-steroidal axially chiral diols as ligands for the asymmetric addition of diethylzinc to aldehydes

Authors
Kostova, K Genov, M Philipova, I Dimitrov, V
Citation
K. Kostova et al., New bis-steroidal axially chiral diols as ligands for the asymmetric addition of diethylzinc to aldehydes, TETRAHEDR-A, 11(16), 2000, pp. 3253-3256
Citations number
20
Categorie Soggetti
Organic Chemistry/Polymer Science
Journal title
TETRAHEDRON-ASYMMETRY
ISSN journal
09574166 → ACNP
Volume
11
Issue
16
Year of publication
2000
Pages
3253 - 3256
Database
ISI
SICI code
0957-4166(20000825)11:16<3253:NBACDA>2.0.ZU;2-T
Abstract
New axially chiral steroidal binaphthols, prepared from estrone, were appli ed in the form of their Ti-alkoxides as catalysts for the addition of dieth ylzinc to aldehydes. The addition reactions proceeded with high yields and enantioselectivities up to 86%. (C) 2000 Elsevier Science Ltd. All rights r eserved.