K. Kostova et al., New bis-steroidal axially chiral diols as ligands for the asymmetric addition of diethylzinc to aldehydes, TETRAHEDR-A, 11(16), 2000, pp. 3253-3256
New axially chiral steroidal binaphthols, prepared from estrone, were appli
ed in the form of their Ti-alkoxides as catalysts for the addition of dieth
ylzinc to aldehydes. The addition reactions proceeded with high yields and
enantioselectivities up to 86%. (C) 2000 Elsevier Science Ltd. All rights r
eserved.