Background. Concepts to make coronary artery bypass operations less in
vasive include minimization of access incisions, elimination of cardio
pulmonary bypass, and no manipulation of the aorta. A spectrum of mini
mally invasive coronary bypass procedures now exist that eliminate the
median sternotomy (port-access approach), cardiopulmonary bypass (''o
ff-pump bypass''), or both (minimally invasive direct coronary artery
bypass procedure). Although all have advantages in decreasing the morb
idity of myocardial revascularization, significant limitations exist i
ncluding surgeon experience, access, exposure, visualization, hemodyna
mic support, and technique of anastomosis. Methods. In an attempt to e
xtend the applicability of the current minimally invasive techniques,
efforts are being made both to extend the indications for the procedur
e as well as to modify the technical aspects. Our current experimental
protocol involves a ports-only approach with three-dimensional video
imaging, percutaneous Hemopump circulatory support, Octopus coronary i
mmobilization, and an endoscopically sutured coronary anastomosis. Res
ults. In a series of animal studies we have been able to successfully
accomplish a totally endoscopic coronary artery bypass procedure on a
beating heart without cardiopulmonary bypass. Conclusions. Although en
doscopic coronary artery bypass without cardiopulmonary bypass is poss
ible, many technical challenges remain. Three-dimensional video imagin
g, wall motion immobilization and presentation, and an axial-flow devi
ce can facilitate the procedure. Future enabling technology including
motion robotics and nonvisual imaging systems may ultimately further m
inimize the invasiveness of surgical myocardial revascularization. (C)
1997 by The Society of Thoracic Surgeons.