Es. Chun et al., COLOSPLENIC FISTULA IN A PATIENT TREATED WITH INTERLEUKIN-2 FOR MALIGNANT-MELANOMA, Journal of computer assisted tomography, 21(4), 1997, pp. 674-676
Interleukin-2 (IL-2) therapy often causes gastrointestinal side effect
s and at least 8 cases of bowel perforation have been reported. The pa
tient reported here developed a colosplenic fistula, diagnosed by CT,
with no neoplastic involvement of these organs. Awareness of these com
plications of IL-2 can help lead to earlier diagnosis.