Spectrophotometric (UV) and chromatographic (HPLC) methods for determination of loratadine hydrochloride in pharmaceutical preparations. Validation of the methods
M. Nogowska et al., Spectrophotometric (UV) and chromatographic (HPLC) methods for determination of loratadine hydrochloride in pharmaceutical preparations. Validation of the methods, CHEM ANAL, 45(5), 2000, pp. 681-688
Spectrophotometric (UV) and chromatographic (HPLC) methods were applied to
the determination of loratadine hydrochloride in tablets and in suspension.
The use of the HPLC method required the optimization of the composition of
the mobile phase. The relationship between drug concentrations and peaks a
rea, the accuracy, precision were rested by using the reference model mixtu
res.