Authors
Citation
J. Glauser, Tricyclic antidepressant poisoning, CLEV CLIN J, 67(10), 2000, pp. 704
Citations number
37
Categorie Soggetti
General & Internal Medicine
Journal title
CLEVELAND CLINIC JOURNAL OF MEDICINE
ISSN journal
08911150
→ ACNP
Volume
67
Issue
10
Year of publication
2000
Database
ISI
SICI code
0891-1150(200010)67:10<704:TAP>2.0.ZU;2-V
Abstract
Tricyclic antidepressant poisoning causes predictable electrocardiographic
abnormalities and can be lethal, Cardiac arrhythmias, hypotension, seizures
, and coma are common. Sodium bicarbonate is still considered the treatment
of choice for severe toxicity, although a variety of supportive measures m
ay be taken. Hypertonic saline appears to be a promising alternative.