A tailored perioperative blood transfusion might avoid undue recurrences in gastric carcinoma patients

Citation
Dk. Dhar et al., A tailored perioperative blood transfusion might avoid undue recurrences in gastric carcinoma patients, DIG DIS SCI, 45(9), 2000, pp. 1737-1742
Citations number
24
Categorie Soggetti
Gastroenerology and Hepatology","da verificare
Journal title
DIGESTIVE DISEASES AND SCIENCES
ISSN journal
01632116 → ACNP
Volume
45
Issue
9
Year of publication
2000
Pages
1737 - 1742
Database
ISI
SICI code
0163-2116(200009)45:9<1737:ATPBTM>2.0.ZU;2-D
Abstract
In a large retrospective study, the prognostic significance of blood transf usion (BT) and type of blood product transfused were searched in 640 curati vely resected gastric carcinoma patients. Out of 640 patients, 222 (34.7%) received BT and the incidence of BT was reduced from 45% in the early perio d to 21% in the most recent period. The five-year disease-free survival was significantly (P < 0.0001.) worse in the transfused group and BT became an independent prognosticator (P = 0.0061) in the multivariate analysis. Pati ents transfused with only packed red blood cells (PRBC)]had significantly ( P = 0.0258) better survival than those transfused with other types of blood products. In conclusion, BT was found to be an independent prognosticator in gastric carcinoma patients after curative resection. A tailored transfus ion with PRBC, when indicated, might be the choice for better survival than whole blood or other blood products.