EVALUATION OF COMMERCIALLY AVAILABLE ASSAYS OF NEOPTERIN AND BETA(2)-MICROGLOBULIN FOR THE ASSESSMENT OF DISEASE PROGRESSION IN FIV-INFECTED CATS

Authors
BEATTY JA WILLETT B DALGLEISH A JARRETT O
Citation
Ja. Beatty et al., EVALUATION OF COMMERCIALLY AVAILABLE ASSAYS OF NEOPTERIN AND BETA(2)-MICROGLOBULIN FOR THE ASSESSMENT OF DISEASE PROGRESSION IN FIV-INFECTED CATS, Veterinary immunology and immunopathology, 56(1-2), 1997, pp. 185-189
Citations number
16
Categorie Soggetti
Immunology,"Veterinary Sciences
Journal title
Veterinary immunology and immunopathology → ACNP
ISSN journal
01652427
Volume
56
Issue
1-2
Year of publication
1997
Pages
185 - 189
Database
ISI
SICI code
0165-2427(1997)56:1-2<185:EOCAAO>2.0.ZU;2-W
Abstract
Serum or plasma samples from cats at different stages of feline immuno deficiency (FIV) infection and from uninfected cats were tested using immunoassays designed to detect human neopterin and beta(2)-microglobu lin (beta(2)M), The results obtained from the anti-human neopterin ass ay did not correlate with infection status, time post-infection, fCD4 count or clinical picture. Feline samples gave negative results in the anti-human beta(2)M assay. The assay kits used in this study are not suitable for the determination of the effect of FIV infection on immun e activation markers in the cat. (C) 1997 Elsevier Science B.V.