Leiomyomata of the uterus are common tumors of women, and a number of treat
ments are now available for symptoms of this disorder. Surgical treatments
include hysterectomy, abdominal myomectomy, laparoscopic myomectomy, and my
olysis. Nonsurgical treatments include uterine artery embolization and medi
cal therapy. All have a small amount of accumulated data, but existing stud
ies are generally small and of poor quality. There is a strong need for app
ropriately designed and analyzed randomized clinical trials, and surgical t
rials should preferably be multicenter/multisurgeon. In summary, although a
large array of options exist, there are still little data upon which to ba
se decisions regarding optimal treatment approaches.