The phase behavior of binary fluid mixtures of hard hyperspheres in four an
d five dimensions is investigated. Spinodal instability is found by using a
recent and accurate I,rescription for the equation of state of the mixture
that requires the equation of state of the single component fluid as input
. The role played by the dimensionality on the possible metastability of th
e demixing transition with respect to a fluid-solid transition is discussed
. The binodal curves in the pressure-chemical potential representation are
seen to lie on a common line, independent of the size ratio.