A flow injection chemiluminescence system for the determination of isoniazid

Authors
Huang, YM Zhang, ZJ Zhang, DJ Lv, J
Citation
Ym. Huang et al., A flow injection chemiluminescence system for the determination of isoniazid, FRESEN J AN, 368(4), 2000, pp. 429-431
Citations number
17
Categorie Soggetti
Spectroscopy /Instrumentation/Analytical Sciences
Journal title
FRESENIUS JOURNAL OF ANALYTICAL CHEMISTRY
ISSN journal
09370633 → ACNP
Volume
368
Issue
4
Year of publication
2000
Pages
429 - 431
Database
ISI
SICI code
0937-0633(200010)368:4<429:AFICSF>2.0.ZU;2-S
Abstract
A chemiluminescence (CL) flow system is described for the determination of isoniazid based on its enhancement on the chemiluminescence (CL) emission p roduced upon mixing a hexacyanoferrate(III) solution with an alkaline lumin ol solution. The system responds linearly to isoniazid concentration in the range 0-1 mg/L with a detection limit (3 sigma) of 0.03 mug/L, relative st andard deviation (RSD) of 1.2% for 0.1 mg/L isoniazid (n = 11). The system has been successfully applied to the determination of isoniazid in pharmace utical preparations.