Osteopontin (Eta-1) in cell-mediated immunity: teaching an old dog new tricks

Authors
O'Regan, AW Nan, GJ Chupp, GL Berman, JS
Citation
Aw. O'Regan et al., Osteopontin (Eta-1) in cell-mediated immunity: teaching an old dog new tricks, IMMUNOL TOD, 21(10), 2000, pp. 475-478
Citations number
18
Categorie Soggetti
Immunology
Journal title
IMMUNOLOGY TODAY
ISSN journal
01675699 → ACNP
Volume
21
Issue
10
Year of publication
2000
Pages
475 - 478
Database
ISI
SICI code
0167-5699(200010)21:10<475:O(ICIT>2.0.ZU;2-C
Abstract
Previously regarded as an adhesive bone matrix protein, recent studies sugg est that osteopontin (Eta-1) is also a novel RGD-containing cytokine that r egulates early cell-mediated immunity. Proteins related to the extracellula r matrix may function as important modulators of immune responses.